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CBB-1007 hydrochloride
InChiKey: COCMHKNAGZHBDZ-UHFFFAOYSA-N
CBL0137 (Curaxin-137) is an inhibitor of the histone chaperone FACT (facilitates chromatin transcription) that simultaneously suppresses NF-κB and activates p53 with EC50 of 0
Smiles: CC1CC[C@@H]2[C@H](OC(=O)C2=C)[C@H]2O[C@]2(C)CCC=1 |c:19|
CAS Number: 1202916-90-2
(-)-Cevimeline hydrochloride Catalog No.:M8813-2 CBB-1007 hydrochloride( ) Cevimeline hydrochloride hemihydrate (( ) SNI 2011), a novel muscarinic receptor agonist, is a candidate therapeutic drug for xerostomia in Sjogren's syndrome. IC50 value: Target: mAChR The general pharmacol. properties of this drug on the gastrointestinal, urinary, and reproductive systems and other tissues were investigated in mice, rats, guinea pigs, rabbits, and dogs. The in vitro metab. of SNI 2011 was also evaluated with rat and dog liver
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